Diablo II: Lord of Destruction is an expansion to Diablo II. It adds Act V which concludes the overarching story, offers a new area with more powerful enemies and six quests to achieve.

After the demonic brothers Diablo and Mephisto were finally defeated, the heroic adventurer who has accomplished that feat returned to the Pandemonium Fortress, summoned by Archangel Tyrael. The third evil brother, Baal, has survived by obtaining his Soulstone. He has raised an army and attacked Mount Arreat in the Barbarian Highlands. The protagonist must venture there and defeat Baal once and for all.